2. Of ANTIOCH. Macedonius, a Monothelite, was patriarch of Antioch from A. D. 639 or 640, till 655 or later. He was appointed to the patriarchate by the influence, if not by the nomination, of Sergius, patriarch of Constantinople, by whom also he was consecrated. The year of his death is not certain. Macarius, who was his successor (though perhaps not immediately), stated in his read at the sixth general council, A. D. 681 [MACARIUS, No. 4], that Macedonius was present at a synod held while Peter was patriarch of Constantinople, i e. some time from A. D. 655 to 666, which shows he could not have died before 655. Macedonius appears to have spent the whole of his patriarchate at Constantinople, Antioch being in the power of the Saracens. (Le Quien, Oriens Christian. vol. ii. col. 740, 741; Bolland. Acta Sanctor. Julii, vol. iv. Tractat. Praelim. p. 109.)